If you miss a dose, don’t stop PrEP, just continue taking it once you remember. You should try and take PrEP at the same time every day. For people who routinely have sex at least once a week, daily PrEP is likely to be a better dosing option. This means you do not have to plan when to have sex. Taking PrEP every day will make sure that there are protective drug levels in vaginal and anal tissue, 24 hours a day, 7 days a week. event based dosing (taking PrEP around the time of sex).There are 2 different ways you can take PrEP, depending on your circumstances and how often you have sex: Read about why being tested for HIV and STIs is important when you are taking PrEP. Once you start taking PrEP, you need to be tested and monitored regularly. As the body takes a while to absorb medicines, this means PrEP needs to be taken both before sex and for several days afterwards. For PrEP to be most effective, the medicine needs to be at protective levels at the time that HIV exposure may happen.